Low Nitric Oxide (NO) isn't always the first change you'll notice. Your body often sends out other physical signals first—warning signs that something deeper is affecting your hormones, energy, and overall performance. Ignoring them can make it harder to restore balance later.
1. Fatigue or low energy levels
On average, we lose 10 percent of our body’s ability to make nitric oxide for every decade of life. By the age of 40, studies show that we make 50% less Nitric oxide than we did as a teenager. [1]
2. High Blood Pressure or decreased heart function & congestive heart failure
Nitric Oxide supports, opens, and expands blood vessels, increases blood circulation and blood flow, at the same time decreasing plaque build-up and blood clotting. Any lifestyle no-no that decreases nitric oxide, such as smoking, high blood pressure, and high cholesterol levels, causes both problems and can lead to congestive heart failure. [2]
3. Anxiety, irritability, or depression
Nitric Oxide is important for brain function and general all-around brain health. Nitric Oxide acts as a messenger molecule that increases healthy blood flow to the brain and forms new brain synapses helping the signals from the brain to pass from one neuron to the next smoothly and efficiently. [7]
4. Erectile Dysfunction (E.D.)
Someone with (E.D.) could get support from the use of Nitric Oxide. Remember that Male Erections depend on realizing and processing of Nitric Oxide among other things. When the body senses overall stress, poor exercise, and general smoking less and less nitric oxide is produced. Do not ignore the signs! Insufficient nitric oxide production can cause endothelium dysfunction, which can contribute to high blood pressure, atherosclerosis, and other risk factors for heart disease. [2]
5. Decreased workout potential or less energy at the gym
After a workout aches and pain are common symptoms of diminished nitric oxide levels. Aches, soreness, and pain are anything but normal for a healthy body. When your cells need oxygen, and your body isn’t getting the blood flow it needs, it may lead to pro-inflammatory cells that are not being flushed out. [5] [6]
6. Vision
Poor Vision problems can be a symptom related to low nitric oxide. The term is called intraocular pressure. In this process, Nitric Oxide is used to regulate the eye fluid called Vitreous humor or Aqueous by determining the proper flow of fluid. The gas nitric oxide carries the fluid where it needs to go. If the fluid is not drained properly, the complex processes will have pressure build-up and can result in weak vision. This might be a good time to get on your Dietary Nitrate intake. [4]
7. Poor lung function
Nitric Oxide is a gas that supports and improves blood flow throughout the areas of the lungs that are getting air by increasing a load of oxygen in the bloodstream. At the same time reducing the workload of the right side of the heart helping the lungs in extreme stress during lung failure. As well as (NO) being used to treat lung failure, it also has been found to have antiviral properties. [3]
Conclusion
A drop in Nitric Oxide is rarely an isolated issue—it's often part of a bigger shift affecting your energy, blood flow, mental focus, and recovery. Addressing these physical changes early can help you maintain vitality and restore balance.
